autoimmune diseases that are linked

Here’s a list of autoimmune conditions that are often linked together, as individuals with one autoimmune disease have a higher risk of developing another. These conditions frequently cluster due to shared genetic, environmental, and immune dysregulation factors.

✅ Commonly Linked Autoimmune Conditions

1. Autoimmune Thyroid Diseases (AITDs)

• Hashimoto’s thyroiditis

• Graves’ disease

• Often associated with: Type 1 diabetes, celiac disease, and systemic lupus erythematosus (SLE).

2. Type 1 Diabetes (T1D)

• Frequently linked to:

• Celiac disease

• Autoimmune thyroid diseases

• Addison’s disease

• Rheumatoid arthritis (RA)

3. Celiac Disease

• Common comorbidities:

• Type 1 diabetes

• Hashimoto’s thyroiditis

• Sjögren’s syndrome

• Multiple sclerosis (MS)

4. Rheumatoid Arthritis (RA)

• Often associated with:

• SLE

• Sjögren’s syndrome

• Autoimmune thyroid diseases

• Psoriasis

5. Systemic Lupus Erythematosus (SLE)

• Linked to:

• RA

• Sjögren’s syndrome

• Antiphospholipid syndrome (APS)

• Autoimmune thyroid diseases

6. Multiple Sclerosis (MS)

• Frequently co-occurs with:

• Celiac disease

• Thyroid disorders

• Inflammatory bowel disease (IBD)

7. Inflammatory Bowel Diseases (IBD)

• Includes Crohn’s disease and ulcerative colitis

• Often linked to:

• Psoriasis

• Ankylosing spondylitis

• Primary sclerosing cholangitis (PSC)

8. Psoriasis and Psoriatic Arthritis

• Frequently linked with:

• IBD

• RA

• SLE

9. Sjögren’s Syndrome

• Common comorbidities:

• RA

• SLE

• Scleroderma

• Autoimmune thyroid diseases

10. Antiphospholipid Syndrome (APS)

• Often secondary to:

• SLE

• Linked to clotting disorders and pregnancy complications

🧬 Other Linked Clusters

• Polyautoimmunity: When a person has two or more autoimmune diseases.

• Multiple Autoimmune Syndrome (MAS): When a person has three or more autoimmune conditions, often involving thyroid, skin, and systemic diseases.